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Marijuana brings on the munchies. What about CBD in food?

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As a dietitian, I always receive an influx of new year’s emails predicting upcoming food trends. This year, several experts have forecast an increase in foods and beverages containing cannabidiol, a chemical compound found in cannabis plants.

More colloquially called CBD, cannabidiol has been approved by the Food and Drug Administration to treat some forms of epilepsy and shows potential in treating pain, nausea, anxiety and depression — without making users high.

If pot use leads to the munchies, some question if a trend toward CBD-infused foods lead to weight gain.
If pot use leads to the munchies, some question if a trend toward CBD-infused foods lead to weight gain.  (Luis Mora photo)

But what about its effect on hunger? After all, smoking or ingesting cannabis is associated with the munchies. Does CBD have the same effect? Could a trend toward CBD-infused foods lead to weight gain? And how might CBD affect people who have conditions that make it difficult to keep weight on (such as those with HIV/AIDS, cancer, eating disorders or depression)? I consulted some experts.

To understand their answers to these questions, first, a quick tutorial. Cannabis plants contain more than 100 cannabinoids, although the therapeutic and psychoactive effects of most of them aren’t yet known. The two most-researched cannabinoids are CBD and tetrahydrocannabinol, or THC, which is the main psychoactive cannabinoid. THC makes you high; CBD doesn’t. And, it turns out, they affect appetite in different ways.

THC produces the well-known cravings for sweet and fatty foods through several mechanisms, according to the experts I consulted. First, “THC increases the hormone ghrelin, which causes you to feel hungry,” says Janice Newell Bissex, a registered dietitian and holistic cannabis practitioner in Melrose, Mass. If your stomach is empty, she says, you produce more of the hunger hormone ghrelin, which tells the brain to generate the sensation of hunger. But THC can increase ghrelin and trigger the feeling of hunger even if your stomach isn’t empty.

Second, THC hits a part of the brain that controls hunger. “The appetite-promoting effect of THC is mediated by CB1 receptors located in areas of the brain involved in appetite control,” explains George Kunos, scientific director at the National Institute on Alcohol Abuse and Alcoholism in the National Institutes of Health in Bethesda, Md.

And, third, THC boosts dopamine, the “feel-good” chemical in the brain, “so you get more pleasure from eating,” Bissex says. “THC can increase the sense of smell and taste, so people are more inclined to want to eat.”

CBD, by contrast, does not cause the munchies, the experts said. But it may boost appetite in a different way if it’s added to foods and beverages or taken as a medication. “CBD helps relieve nausea and can calm your nervous system and digestive tract” Bissex says. “If you feel less nauseated, you may eat more. CBD also quells pain, and feeling less pain may also boost appetite.” For that reason, it’s often used by people with cancer, chronic pain or other medical issues. (Either CBD or THC — or both — can be found in medical marijuana products.)

If THC increases appetite, does that mean recreational cannabis users will weigh more than nonusers because they want to keep eating? You’d think so, but surprisingly the answer is no.

“Studies indicate that regular heavy cannabis users tend to be leaner than age- and gender-matched groups of nonusers,” Kunos says.

Overall, cannabis use in the general population is actually associated with a lower body mass index. “Interestingly, cannabis may help increase weight in those who are low weight, but not in those who are normal or overweight,” says Bissex.

The reason has not been definitively established, but may involve the amount of THC that someone is exposed to, says Kunos says. High doses of THC can suppress the number of CB1 receptors so that fewer receptors are stimulated, which could limit weight gain.

And, THC’s hunger-boosting effect may signal hope for weight-loss efforts. Because researchers are able to figure out how cannabis increases appetite, it may help them develop products to reduce appetite, too. Some drugs are “inverse agonists,” which means that they bind to the same area in the brain but produce an opposite response. Using this theory, researchers are investigating how to reduce, rather than increase, appetite using CB1 receptors.

In 2006, a drug called rimonabant held potential to be an effective inverse agonist to aid weight loss, but it had too many psychiatric side effects and was pulled off the market. Kunos’s lab is working on an appetite-suppressant drug without the side effects.

So, are the food trends experts on to something? Will CBD be on the menu at your favourite restaurants and on store shelves where you buy groceries? In the U.S., that will depend on where you live. If you live in Oregon, California, New York or Colorado, you may very well be ordering CDB-infused beer, or buying CBD-enhanced sweets and pastries. You can rest assured that such products will not cause the munchies — but keep in mind that weight gain could result from consuming the beer, sweets and pastries themselves.

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Post-vaccine surge? Michigan’s spring coronavirus case spike close to previous year’s autumn high

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(Natural News) The spike in new Wuhan coronavirus infections recorded in Michigan over the spring is similar to a spike seen during the 2020 fall season. According to a Wall Street Journal analysis, the state’s daily coronavirus case count averaged more than 7,000 for almost two weeks – before taking a slight dip to 6,891 on April 20. This echoed similar figures back in November and December 2020, which saw sharp rises in infections for those two months before plunging.

Back in autumn of last year, Michigan averaged more than 7,000 cases per day for a span of 10 days. New infections dropped slightly, then briefly spiked as the December holidays approached. It then fell to the low 1,000s for the succeeding two months – until ascending again in March.

According to University of Michigan internal medicine professor Dr. Vikas Parekh, the sudden increase in new infections could be attributed to several factors. Among the factors he cited was re-openings, which increased people’s interactions and mobility. Parekh said the loosened restrictions contributed to the spread of the highly contagious U.K. B117 variant.

“As the B117 variant spreads nationally, we will likely see other stats [with] their own surges – although I hope none are as bad as Michigan,” the professor remarked. He continued: “The milestone just tells us we are not yet in the clear, especially as we still have large portions of our population who are not vaccinated yet.”

Parekh also expressed optimism over the lower daily caseloads the Great Lakes State reported. He said he believes both cases and hospitalizations have plateaued and will likely decline soon. The professor commented: “[COVID-19] positivity has been declining now for one week, which is usually a leading indicator of case decline.”

Meanwhile, the state cited younger populations and youth sports, such as basketball, wrestling and hockey, to increase new COVID-19 infections. Because of this, Gov. Gretchen Whitmer called to suspend youth sports and indoor dining in the state. She also exhorted high schools to conduct remote class sessions for two weeks to curb the spread of the pathogen.

Michigan still experienced the spike in cases despite having one of the highest vaccination rates in the country

During the opening stages of the U.S.’s immunization drive against COVID-19, Michigan boasted of having one of the highest vaccination rates nationwide. A report by Bridge Michigan even noted the initial “frenzy for vaccines” that “far exceeded the state’s limited supply.” But things have appeared to turn around for Michigan, as it now struggles to reach the 70 percent vaccination rate needed for herd immunity.

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Scottish mom’s legs turn into a pair of “giant blisters” after first dose of AstraZeneca’s coronavirus vaccine

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(Natural News) Sarah Beuckmann of Glasgow, Scotland, felt a tingling sensation in her legs and noticed a rash flaring up around her ankles a week after getting her first dose of AstraZeneca’s coronavirus (COVID-19) vaccine on March 18.

She also had flu-like symptoms right after the vaccination.

Beuckmann called her doctor to arrange an appointment the morning she noticed the rash, but by the afternoon her skin was already breaking out into blood-filled blisters. Blisters also appeared on her legs, hands, face, arms and bottom.

“I ended up asking my husband to take me to A&E,” said Beuckmann, referring to “accident and emergency,” the equivalent of an emergency room (ER). “When I got there, my heart rate was sitting at 160bpm, which they were very concerned about. I got put on an ECG machine.”

Doctors determine AstraZeneca’s COVID-19 vaccine triggers the rash

Medics carried out tests for HIV, herpes and other skin conditions to work out what triggered the rash, but all results came back negative. Doctors finally determined that the vaccine caused her rare reaction after carrying out two biopsies.

“Once they found that it was a reaction to the vaccine, they put me on steroids and that really seems to be helping my progress,” said Beuckmann. She had been advised by her doctor not to get the second dose of AstraZeneca’s COVID-19 vaccine because of her reaction.

Beuckmann spent 16 days at Queen Elizabeth University Hospital. She was discharged to recover at home. The 34-year-old mother of one is currently wheelchair-bound due to the bandages on her legs and blisters on the soles of her feet. She may need physiotherapy to help strengthen her leg muscles.

“They are starting to heal and they’re looking a lot better than they were but as the blisters started to get worse, they all sort of merged together,” she said. “I didn’t know what was going on.”

With the blisters merging, her legs have looked like a pair of “giant blisters.” Beuckmann admitted that at one point she feared her legs might have to be amputated.

Dermatologist agrees COVID-19 vaccine causes the blisters

Dr. Emma Wedgeworth, a consultant dermatologist and spokeswoman at the British Skin Foundation, agreed that Beuckmann had likely suffered a reaction to the vaccine.

“Vaccines are designed to activate the immune system. Occasionally people will have quite dramatic activation of their immune systems which, as happened in this case, can manifest in their skin” Wedgeworth told MailOnline. “This poor lady had a very severe reaction, which thankfully is extremely rare.”

It is not clear why Beuckmann, who works in retail, was invited for a vaccine. Scotland’s vaccine rollout was focused on people over the age of 50 when she got vaccinated, although vaccines are available to those who are considered at risk from the virus, or live with someone considered vulnerable.

At least 20 million Briton have had AstraZeneca’s COVID-19 vaccine, which drug regulators say causes a rash in one percent of cases. They say rashes caused by the jab tend to go away within a week.

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Trojan labs? Chinese biotech company offers to build COVID testing labs in six states

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In 2012, BGI acquired Complete Genomics, a DNA sequencing company and equipment maker. The funds for the $117.6 million purchase were raised from Chinese venture capitals. The company has expanded its footprint globally. According to its website, BGI conducts business in more than 100 countries and areas and has 11 offices and labs in the U.S.

People are concerned about China’s access to American DNA data

Some said that with Complete Genomics providing an American base, BGI would have access to more DNA samples from Americans, helping it compile a huge database of genetic information. Some also worried about the protection of the genetic information’s privacy.

According to a 2019 report from the U.S.–China Economic and Security Review Commission (USCC), BGI “has formed numerous partnerships with U.S. healthcare providers and research organizations to provide large-scale genetic sequencing to support medical research efforts,”

There are three main reasons why many people in the biotech community and government have expressed concerns about China’s access to American DNA data.

In the “60 Minutes” interview, Evanina discussed the very likely scenario in which Chinese companies would be able to micro-target American individuals and offer customized preventative solutions based on their DNA.

Evanina asked: “Do we want to have another nation systematically eliminate our healthcare services? Are we okay with that as a nation?”

The second concern is that China may use DNA to track and attack American individuals. As the USCC report states: “China could target vulnerabilities in specific individuals brought to light by genomic data or health records. Individuals targeted in such attacks would likely be strategically identified persons, such as diplomats, politicians, high-ranking federal officials or military leadership.”

The third concern is that China may devise bioweapons to target non-Asians. Steven Mosher, president of the Population Research Institute, discussed it in his article “What Will China Do With Your DNA?” published by The Epoch Times in March 2019.

He wrote: “We know that the Asian genome is genetically distinct from the Caucasian and African in many ways. … Would it be possible to bioengineer a very virulent version of, say, smallpox, that was easily transmitted, fatal to other races, but to which the Chinese enjoyed a natural immunity? … Given our present ability to manipulate genomes, if such a bio-weapon can be imagined, it can probably – given enough time and resources – be realized.”

An article from Technocracy said: “China’s aggressive collection of American DNA should be doubly alarming because it can only spell one ultimate outcome: biowarfare. That is, genetically engineering viruses or other diseases that will be selectively harmful to U.S. populations.”

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