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Your Definitive Guide to Dietary Fats

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Whereas my book “Fat for Fuel” details how to implement a cyclical ketogenic diet, my latest book, cowritten with James DiNicolantonio, Pharm.D., “Superfuel: Ketogenic Keys to Unlock the Secrets of Good Fats, Bad Fats, and Great Health,” delves further into the science of dietary fats, providing specifics on how to discriminate between healthy and harmful ones.


Superfuel

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The importance of this cannot be overstated, as fats are truly an extraordinary fuel for your body and brain, yet unhealthy fats can do more harm than excess sugar.

Unfortunately, most doctors are still clueless about this, and the U.S. dietary guidelines are leading people in the complete opposite direction of health with regard to dietary fats. Hence, the incentive for writing “Superfuel,” the release of which we celebrate today, just in time for Black Friday!

Omega-3 — The Healthy Fat Most People Don’t Get Enough Of

One of the most important fats in the human diet is marine-based omega-3. Unfortunately, in the past 100 years, our omega-6 intake has nearly tripled, largely due to misleading or outright incorrect marketing and government health campaigns, while our intake of omega-3 has decreased 10fold, causing a severe imbalance in our omega-3 to omega-6 ratio.

Ideally, you want to maintain a 4-to-1 ratio of omega-6 and omega-3 fats or less, which is nearly impossible if you’re regularly eating processed foods or restaurant fare, as these are loaded with omega-6 from industrial vegetable oils like corn oil and canola oil. While you clearly need some omega-6s, they need to be unprocessed (think whole, raw plant seeds and tree nuts), and that cannot be said for most commercial vegetable oils.

One of the most significant dangers of vegetable oils is that the damaged fats are integrated into your cell and mitochondrial membranes, and once these membranes are impaired, it sets the stage for all sorts of health problems.

As just one example, explained by DiNicolantonio, the inner membrane of your mitochondria contains a component called cardiolipin, which needs to be saturated in the omega-3 fat docosahexaenoic acid (DHA) in order to function properly.

The DHA in cardiolipin can be likened to a cellular alarm system with its oxidation triggering programmed cell death (apoptosis) by signaling caspase-3 when something goes wrong with the cell. However, if the cardiolipin is not saturated with DHA, it cannot signal caspase-3, and apoptosis does not occur. As a result, dysfunctional cells continue to grow and may turn into a cancer cell.

DHA Is Crucial for Your Brain; EPA for Your Heart

It’s also crucial to realize that the marine-based omega-3 fats DHA and eicosapentaenoic acid (EPA) are not just fuel. These long-chained omega-3s are actually key structural elements of all cells, including your brain cells. If you don’t have enough DHA and EPA, your body’s ability to repair and maintain healthy cell structures is seriously impaired.

DHA is particularly crucial for your brain. Not only does it stimulate Nrf21 (a transcription factor that regulates cellular oxidation and reduction, and aids in detoxification), it also increases heme oxygenase 12 (a protein produced in response to oxidative stress) and upregulates antioxidant enzymes.

EPA, meanwhile, appears to be the most crucial component for your heart, and has been linked to a lower risk for heart disease. Most recently, a study3 involving a highly-processed form of EPA found it lowered cardiovascular health risks by 25 percent compared to a placebo, which is typically the kind of reduction you see with the use of statins.

Perhaps one of the most important pieces of data from this trial is the dosage used. While most studies use doses around a single gram per day, the REDUCE-IT trial used a daily dose of 3 to 4 grams.

The strong beneficial effect seen at this higher dosage confirms and supports health predictions made in “Superfuel,” where we note that most people need far higher dosages than commonly recommended (although the only way to be sure is to measure your omega-3 blood level).

As general guidance, however, you only need around 1 to 2 grams of omega-6 linoleic acid per day, ideally from plant seeds and tree nuts, whereas optimal levels of marine omega-3 fats are around 3 to 4 grams per day.


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Krill Oil, Phospholipids and Your Brain

As you probably know, small fatty fish such as anchovies, sardines and mackerel are excellent sources of EPA and DHA. Unfortunately, industrial processing practices render most fish oils far from ideal. This is a topic we examine at greater depth in “Superfuel.” A summary of some of the key issues can also be found in my previous article, “Are Many Fish Oils Synthetic?

About half of all fish oil supplements also have problems with oxidation. When buying a fish oil supplement, I recommend looking for a product that tests the hydroperoxide levels, and has a level below 5 percent.

An alternative source that bypasses these quality problems is krill oil. Aside from being far less prone to oxidation (courtesy of natural astaxanthin, a powerful antioxidant with major health benefits of its own), the omega-3s in krill oil are also bound to phospholipids, and this gives krill oil distinct health advantages over fish oil, in which the DHA/EPA are bound to triglycerides.

Fatty acids such as DHA and EPA are water insoluble and therefore cannot be transported in their free form in your blood, which is primarily water. They must be packaged into lipoprotein vehicles such as phospholipids. This is primarily why the bioavailability of krill oil is so much higher than fish oil. When you consume fish oil, your liver has to attach it to phosphatidylcholine in order for it to be efficiently utilized by your body and brain.

Phospholipids are also one of the principal compounds in high-density lipoproteins (HDL), which you want more of, and by allowing your cells to maintain structural integrity, phospholipids help your cells function optimally.

Importantly, your brain cannot readily absorb DHA unless it’s bound to phosphatidylcholine, and while krill oil contains phosphatidylcholine naturally, fish oil does not. As the name implies, phosphatidylcholine is composed partly of choline, the precursor for the vital neurotransmitter acetylcholine, which sends nerve signals to your brain, and choline itself is crucial for brain development, learning and memory.

These phospholipids are radically underappreciated and serve as one of the best dietary supplements of phosphatidylcholine, which is essential in detoxification for facilitating excretion out of the liver cells into the gallbladder for elimination in the intestine.

Phospholipid-Bound DHA May Be Ideal for Those at High Risk for Alzheimer’s

Recent research4 by Rhonda Patrick, Ph.D., also highlights the value of DHA bound to phospholipids, showing this form may actually reduce the risk of Alzheimer’s disease in those with the apolipoprotein E4 (APOE4) gene, which is thought to be present in about one-quarter of the population and lowers the typical age of onset of this degenerative brain disorder.

Two hallmarks of Alzheimer’s are amyloid beta plaques and tau tangles, both of which impair normal brain functioning. Alzheimer’s patients also have reduced glucose transport into their brains, and this is one of the reasons why plaque and tangles form and accumulate in the first place.

According to Patrick,5 DHA encourages your brain’s uptake of glucose by regulating the structure and function of glucose transporters, proteins located at your blood-brain barrier.

Curiously, while eating DHA-rich fish has been shown to slow the progression of Alzheimer’s in APOE4 carriers, taking fish oil has not demonstrated the same efficacy. According to Patrick, this variation in response appears to be related to the different ways in which the two forms of DHA are metabolized and ultimately transported into your brain.

When the triglyceride form of DHA is metabolized, most of it turns into nonesterified DHA, while the phospholipid form is metabolized primarily into DHA-lysophosphatidylcholine (DHA-lysoPC). While both of these forms can cross the blood-brain barrier to reach your brain, the phospholipid form does so far more efficiently.

According to Patrick, people with APOE4 have a faulty nonesterified DHA transport system, and this may be why they’re at increased risk for Alzheimer’s. The good news is that DHA-lysoPC can bypass the tight junctions, thereby improving DHA transport, and for those with one or two APOE4 variants, taking the phospholipid form of DHA may therefore lower their risk of Alzheimer’s more effectively.

Vegetable Oils — A Bane to Health

While U.S. dietary guidelines still insist vegetable oils are your healthiest bet, this flies in the face of nutritional science, which clearly shows there are serious problems with these oils.

The American Heart Association (AHA) recommends you consume 5 to 10 percent of your calories as omega-6 from vegetable oils. Meanwhile, research6 shows that when you lower omega-6 linoleic acid from over 5 percent to about 3.5 percent, cardiovascular problems and mortality are reduced by a whopping 70 percent. In summary, processed vegetable oils (polyunsaturated fat) harm health by:











Creating high amounts of oxidation products when used in cooking (as they are very susceptible to heat), including aldehydes, which are what causes oxidized low-density lipoprotein (LDL) associated with heart disease. Aldehydes also crosslink tau protein and create neurofibrillary tangles, thereby contributing to the development of neurodegenerative diseases.

Damaging the endothelium (the cells lining your blood vessels) and causing an increase in penetration of LDL and very low-density lipoprotein (VLDL) particles into the subendothelium. As noted by DiNicolantonio, these omega-6 seed oils are “literally transforming you from the inside-out, because these long-chain omegas get integrated in the cell membrane.”

Damaging your mitochondria and DNA by making your cell membranes more permeable, allowing things to enter that shouldn’t.

Making the cell membrane less fluid, which impacts hormone transporters in the cell membrane and slows your metabolic rate.

Inhibiting cardiolipin, an important component of the inner membrane of your mitochondria that needs to be saturated in DHA in order for it to function properly.

Cardiolipin can be likened to a cellular alarm system that triggers apoptosis (cell death) by signaling caspase-3 when something goes wrong with the cell. If the cardiolipin is not saturated with DHA, it cannot signal caspase-3, and hence apoptosis does not occur. As a result, dysfunctional cells are allowed to continue to grow, which can turn into a cancerous cell.

Inhibiting the removal of senescent cells, i.e., aged, damaged or crippled cells that have lost the ability to reproduce.

Stripping your liver of glutathione (which produces antioxidant enzymes), thereby lowering your antioxidant defenses.7

Inhibiting delta-6 desaturase (delta-6), an enzyme involved in the conversion of short-chained omega-3s to longer chained omega-3s in your liver.8

Exposing you to toxic 4-hydroxynonenal (4HNE), which forms during the processing of most vegetable oils, even if the oil is obtained from organic crops. 4HNE is highly toxic, especially to your gut bacteria, and consumption of 4HNE has been correlated with having an obesogenic balance of gut flora. It also causes DNA damage and instigates free radical cascades that damage your mitochondrial membranes.9

Exposing you to glyphosate residues, as most vegetable oils are made with genetically engineered crops. Glyphosate has been shown to disrupt the tight junctions in your gut and increase penetration of foreign invaders, especially heated proteins, which can cause allergies.

Take Control of Your Health by Eating the Right Kinds of Fats

This and much more is covered in “Superfuel: Ketogenic Keys to Unlock the Secrets of Good Fats, Bad Fats, and Great Health,” which is available for shipping as of today. The book can also be ordered from Amazon or Barnes & Noble. It’s a great complement to “Fat for Fuel,” and will help you clearly understand the benefits of these vitally important fats.


buy now

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The following list from Dr. Cate Shanahan, author of “Deep Nutrition: Why Your Genes Need Traditional Food,” also details some of the best and worst fats found in our modern diet.


good and bad fats

>>>>> Click Here <<<<<

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Post-vaccine surge? Michigan’s spring coronavirus case spike close to previous year’s autumn high

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(Natural News) The spike in new Wuhan coronavirus infections recorded in Michigan over the spring is similar to a spike seen during the 2020 fall season. According to a Wall Street Journal analysis, the state’s daily coronavirus case count averaged more than 7,000 for almost two weeks – before taking a slight dip to 6,891 on April 20. This echoed similar figures back in November and December 2020, which saw sharp rises in infections for those two months before plunging.

Back in autumn of last year, Michigan averaged more than 7,000 cases per day for a span of 10 days. New infections dropped slightly, then briefly spiked as the December holidays approached. It then fell to the low 1,000s for the succeeding two months – until ascending again in March.

According to University of Michigan internal medicine professor Dr. Vikas Parekh, the sudden increase in new infections could be attributed to several factors. Among the factors he cited was re-openings, which increased people’s interactions and mobility. Parekh said the loosened restrictions contributed to the spread of the highly contagious U.K. B117 variant.

“As the B117 variant spreads nationally, we will likely see other stats [with] their own surges – although I hope none are as bad as Michigan,” the professor remarked. He continued: “The milestone just tells us we are not yet in the clear, especially as we still have large portions of our population who are not vaccinated yet.”

Parekh also expressed optimism over the lower daily caseloads the Great Lakes State reported. He said he believes both cases and hospitalizations have plateaued and will likely decline soon. The professor commented: “[COVID-19] positivity has been declining now for one week, which is usually a leading indicator of case decline.”

Meanwhile, the state cited younger populations and youth sports, such as basketball, wrestling and hockey, to increase new COVID-19 infections. Because of this, Gov. Gretchen Whitmer called to suspend youth sports and indoor dining in the state. She also exhorted high schools to conduct remote class sessions for two weeks to curb the spread of the pathogen.

Michigan still experienced the spike in cases despite having one of the highest vaccination rates in the country

During the opening stages of the U.S.’s immunization drive against COVID-19, Michigan boasted of having one of the highest vaccination rates nationwide. A report by Bridge Michigan even noted the initial “frenzy for vaccines” that “far exceeded the state’s limited supply.” But things have appeared to turn around for Michigan, as it now struggles to reach the 70 percent vaccination rate needed for herd immunity.

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Scottish mom’s legs turn into a pair of “giant blisters” after first dose of AstraZeneca’s coronavirus vaccine

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(Natural News) Sarah Beuckmann of Glasgow, Scotland, felt a tingling sensation in her legs and noticed a rash flaring up around her ankles a week after getting her first dose of AstraZeneca’s coronavirus (COVID-19) vaccine on March 18.

She also had flu-like symptoms right after the vaccination.

Beuckmann called her doctor to arrange an appointment the morning she noticed the rash, but by the afternoon her skin was already breaking out into blood-filled blisters. Blisters also appeared on her legs, hands, face, arms and bottom.

“I ended up asking my husband to take me to A&E,” said Beuckmann, referring to “accident and emergency,” the equivalent of an emergency room (ER). “When I got there, my heart rate was sitting at 160bpm, which they were very concerned about. I got put on an ECG machine.”

Doctors determine AstraZeneca’s COVID-19 vaccine triggers the rash

Medics carried out tests for HIV, herpes and other skin conditions to work out what triggered the rash, but all results came back negative. Doctors finally determined that the vaccine caused her rare reaction after carrying out two biopsies.

“Once they found that it was a reaction to the vaccine, they put me on steroids and that really seems to be helping my progress,” said Beuckmann. She had been advised by her doctor not to get the second dose of AstraZeneca’s COVID-19 vaccine because of her reaction.

Beuckmann spent 16 days at Queen Elizabeth University Hospital. She was discharged to recover at home. The 34-year-old mother of one is currently wheelchair-bound due to the bandages on her legs and blisters on the soles of her feet. She may need physiotherapy to help strengthen her leg muscles.

“They are starting to heal and they’re looking a lot better than they were but as the blisters started to get worse, they all sort of merged together,” she said. “I didn’t know what was going on.”

With the blisters merging, her legs have looked like a pair of “giant blisters.” Beuckmann admitted that at one point she feared her legs might have to be amputated.

Dermatologist agrees COVID-19 vaccine causes the blisters

Dr. Emma Wedgeworth, a consultant dermatologist and spokeswoman at the British Skin Foundation, agreed that Beuckmann had likely suffered a reaction to the vaccine.

“Vaccines are designed to activate the immune system. Occasionally people will have quite dramatic activation of their immune systems which, as happened in this case, can manifest in their skin” Wedgeworth told MailOnline. “This poor lady had a very severe reaction, which thankfully is extremely rare.”

It is not clear why Beuckmann, who works in retail, was invited for a vaccine. Scotland’s vaccine rollout was focused on people over the age of 50 when she got vaccinated, although vaccines are available to those who are considered at risk from the virus, or live with someone considered vulnerable.

At least 20 million Briton have had AstraZeneca’s COVID-19 vaccine, which drug regulators say causes a rash in one percent of cases. They say rashes caused by the jab tend to go away within a week.

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Trojan labs? Chinese biotech company offers to build COVID testing labs in six states

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In 2012, BGI acquired Complete Genomics, a DNA sequencing company and equipment maker. The funds for the $117.6 million purchase were raised from Chinese venture capitals. The company has expanded its footprint globally. According to its website, BGI conducts business in more than 100 countries and areas and has 11 offices and labs in the U.S.

People are concerned about China’s access to American DNA data

Some said that with Complete Genomics providing an American base, BGI would have access to more DNA samples from Americans, helping it compile a huge database of genetic information. Some also worried about the protection of the genetic information’s privacy.

According to a 2019 report from the U.S.–China Economic and Security Review Commission (USCC), BGI “has formed numerous partnerships with U.S. healthcare providers and research organizations to provide large-scale genetic sequencing to support medical research efforts,”

There are three main reasons why many people in the biotech community and government have expressed concerns about China’s access to American DNA data.

In the “60 Minutes” interview, Evanina discussed the very likely scenario in which Chinese companies would be able to micro-target American individuals and offer customized preventative solutions based on their DNA.

Evanina asked: “Do we want to have another nation systematically eliminate our healthcare services? Are we okay with that as a nation?”

The second concern is that China may use DNA to track and attack American individuals. As the USCC report states: “China could target vulnerabilities in specific individuals brought to light by genomic data or health records. Individuals targeted in such attacks would likely be strategically identified persons, such as diplomats, politicians, high-ranking federal officials or military leadership.”

The third concern is that China may devise bioweapons to target non-Asians. Steven Mosher, president of the Population Research Institute, discussed it in his article “What Will China Do With Your DNA?” published by The Epoch Times in March 2019.

He wrote: “We know that the Asian genome is genetically distinct from the Caucasian and African in many ways. … Would it be possible to bioengineer a very virulent version of, say, smallpox, that was easily transmitted, fatal to other races, but to which the Chinese enjoyed a natural immunity? … Given our present ability to manipulate genomes, if such a bio-weapon can be imagined, it can probably – given enough time and resources – be realized.”

An article from Technocracy said: “China’s aggressive collection of American DNA should be doubly alarming because it can only spell one ultimate outcome: biowarfare. That is, genetically engineering viruses or other diseases that will be selectively harmful to U.S. populations.”

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