Connect with us

Health

Probiotic Wipes Out Dangerous Antibiotic-Resistant Bacteria

Editor

Published

on

[ad_1]

The nearly 100 trillion bacteria living on and in your body perform a wide variety of functions. We have only now come to realize the bacteria must be properly balanced and nourished to maintain good physical and mental health.

Although the Human Genome Project was expected to demonstrate gene-based therapies could rid us of disease, it actually revealed genetic makeup plays a much smaller role than previously imagined. Emerging science also shows your microbiome may be rapidly altered, for better or worse, based on factors such as your diet, lifestyle and chemical exposure.

While this is a double-edged sword, since many modern conveniences are extremely detrimental to gut flora, your diet is likely one of the easiest, fastest and most effective ways to optimize your microbiome. The importance of the bacteria growing in your gut is become increasingly clear as we learn these colonies of microorganisms lend truth to the old adage,1 “you are what you eat.”

Research has demonstrated your gut microbiome plays a significant role in your immune system and in the development of many diseases and health conditions, including obesity and difficulty maintaining weight loss after dieting, depression and multiple sclerosis, just to name a few.

Most recently, a study from National Institutes of Health (NIH) scientists and colleagues have demonstrated a balance of beneficial bacteria in your digestive tract may help protect you against antibiotic-resistant Staphylococcus.2

Staphylococcus Infections Deadly Worldwide

Staphylococcus aureus (S. aureus) is a bacterium commonly found on the skin and nose, even in healthy people. Although it normally doesn’t cause infections or problems, if it invades your body or colonizes your gut, it can create significant problems. S. aureus has also become antibiotic-resistant, and is a common cause of sepsis.

Staph infections can range from skin infections to endocarditis, a potentially deadly infection attacking your heart muscle. As a result, the symptoms of a staph infection are varied, depending upon the system the bacteria is attacking in your body.3

The emergence of methicillin-resistant S. aureus (MRSA) began in the 1960s and disseminated globally, quickly becoming a leading cause of bacterial infections, both within the health care system and community settings.4 MRSA is resistant to several antibiotics, including methicillin, penicillin and amoxicillin.

The resistance makes the infection challenging to treat and increases the risk of death when it triggers sepsis. In the U.S., S. aureus is one of the most common triggers for skin infections, including boils, impetigo, abscesses and wound infections.5

Over 95,000 MRSA infections are diagnosed annually, approximately 18,000 of which result in death.6 Nearly 86 percent of all invasive MRSA infections occur in the health care setting.7 Staphylococcus bacteria are also a common trigger for food poisoning.8 Symptoms usually happen within hours of eating the contaminated food, but often disappear quickly after lasting just 12 hours.

However, when S. aureus enters your blood it may trigger septicemia, including fever, low blood pressure and infections in internal organs, bones, muscles and around surgically implanted devices.

Between 2009 and 2014, the average percentage of S. aureus isolates found to be antibiotic-resistant was nearly 20 percent in the U.S.9 In response, the National Institute of Allergy and Infectious Diseases, sponsored by NIH, investigated the potential of Bacillus (beneficial bacteria used in probiotic supplements) protecting against S. aureus.10

Probiotic Kills Antibiotic-Resistant Bacteria

Bacteria are microscopic, single-celled organisms existing in every environment, both inside and outside of other organisms. Some, like S. aureus, are harmful, but others serve a useful purpose.11 However the proliferation of S. aureus increases your risk of becoming infected with a serious antibiotic-resistant infection.

Unexpectedly, they found Bacillus bacteria prevented S. aureus from growing in the gut and nose of healthy individuals. Bacillus is commonly found in probiotic supplements and may eliminate these bacteria by secreting a compound that blocks a key signaling system known as quorum sensing.12 This signaling mechanism controls the cell’s adaptation to the population density of bacteria.

Different species of bacteria have different signals and sensors, making it possible a substance inhibiting quorum sensing in S. aureus may not affect another bacteria. The bacteria were able to inhibit the specialized system producing molecules known as fengycins.

Using chromatography and mass spectrometry, the scientists identified the fengycins, a class of lipopeptides, as the specific substance inhibiting the sensing system. Fengycins inhibited the growth of S. aureus, including USA300 MRSA, the superbug responsible for most of the life-threatening, community-associated infections in the U.S.13

Bacillus and S. Aureus Were Not Present in the Same Subjects

Researchers first collected and analyzed stool samples from nearly 200 participants in rural areas of Thailand. They hypothesized those living in rural areas would be less exposed to antibiotics or food sterilization than individuals in Western countries.14

An analysis of the samples found 12.5 percent of the subjects had S. aureus in their intestines and 13 percent had the bacteria in their nasal passages. This was striking as it was far lower than the colonization commonly recorded in adults in urban areas, which is 20 percent in the gut and 40 percent in the nose.15

The fecal samples also demonstrated those containing Bacillus did not contain S. aureus and vice versa. The scientists then conducted tests on mice, demonstrating S. aureus bacteria have a specialized system allowing them to colonize within the body. In further experiments using mice, S. aureus was introduced and allowed to colonize in the guts of the rodents.16

They then fed the mice Bacillus subtilis spores once every other day. These rodents were soon free of S. aureus in their gut. The hope is to find a strategy preventing S. aureus from colonizing and thus reducing the potential for staph infections. Some of the current methods for decolonization are controversial as they require considerable amounts of antibiotics and have had limited success.

Michael Otto Ph.D., lead investigator of the study commented:17 “Ultimately, we hope to determine if a simple probiotic regimen can be used to reduce MRSA infection rates in hospitals”

Other Health Benefits of Balanced Gut Microbiome

There are other significant benefits to maintaining a balanced gut microbiome. For instance, scientists in the U.K. took a hard look at the introduction of probiotics to the gut microbiome and found it may help prevent the formation of tumors and even treat existing ones.

In their research,18 they wrote gut bacterial Lactobacillus has the potential for treating colon cancer, the third most common cancer in the U.S. other than skin cancer. Several studies have found factors increasing the incidence of colorectal cancer include lack of exercise, low vegetable and fruit consumption, being overweight or obese and being diagnosed with inflammatory bowel disease.

In short, your gut microbiome plays an impressive role in your overall health, including the potential development of colorectal cancer. Researchers have also found differences in gut microbiota between those who suffer from nonalcoholic fatty liver disease (NAFLD) and lean individuals.19

Those with NAFLD are more likely to have bacterial overgrowth in the small intestines along with increased intestinal permeability. Although there is no way to change the fact certain foods increase your risk for packing on pounds, bacteria also play a major role in facilitating the process.

Foods known to produce metabolic dysfunction and insulin resistance, such as processed foods, fructose, sugar and artificial sweeteners, also decimate beneficial gut bacteria. This may in fact be a mechanism by which these foods promote obesity.

Other research has found a functional link between certain gut microbiota and the onset of Parkinson’s disease. Their data20 demonstrate specific chemicals produced by certain bacteria will worsen the accumulation of proteins in the brain associated with Parkinson’s disease.

Your Gut Faces Increasing Threats From Environmental Factors Each Year

Your gut microbiome is under continuous attack by environment, diet and lifestyle choices. If gut bacteria become imbalanced, it increases your risk for both chronic and acute illnesses. Some of the factors posing the greatest danger to your gut microbiome include:







Refined sugar, especially processed high-fructose corn syrup

Genetically engineered (GE) foods (extremely abundant in processed foods and beverages)

Agricultural chemicals such as herbicides and pesticides. Glyphosate appears to be among the worst

Conventionally raised meats and other animal products; factory farmed animals are routinely fed low-dose antibiotics and GE livestock feed

Antibiotics (use only if absolutely necessary, and make sure to reseed your gut with fermented foods and/or a good probiotic supplement)

NSAIDS (nonsteroidal anti-inflammatory drugs) damage cell membranes and disrupt energy production by mitochondria

Proton pump inhibitors (drugs blocking the production of acid in your stomach, typically prescribed for GERD, such as Prilosec, Prevacid and Nexium)

Chlorinated and/or fluoridated water

Antibacterial soap

Gluten and/or lectins

Pollution

Stress

Fiber and Fermented Foods Are Critical to Your Gut Health

Scientists now understand your gut plays a crucial role in health and disease processes, actually acting as a second brain. Modifying your gut microbiome is an excellent long-term investment in your health and wellness. The consequences of a poorly developed microbiome can affect your mood, emotions, allergies and more.21

The bacterial diversity in your gut begins at birth (baby is “inoculated” as it moves through the birth canal) and is affected by genetics, whether you’re breast- or bottle-fed, and your immediate environment. Later in life, diversity is affected by your food choices. Nourishing beneficial bacteria is a way to maintain your health and one easy way is by eating traditionally fermented foods.

Ideally, you’ll want to include a variety of fermented foods and beverages as each will inoculate your gut with different microorganisms. There are several you can easily make at home, including fermented vegetables, chutneys, condiments, cultured dairy products such as yogurt, kefir and sour cream, as well as fermented fish, such as mackerel and Swedish gravlax.

Foods containing fiber, such as nuts, seeds, fruits and vegetables also help promote better digestive health by feeding your beneficial bacteria. One of the reasons fermented foods are so beneficial is they contain a wide variety of beneficial bacteria.

However, this may not be enough if the rest of your diet is poor. Your gut bacteria are an active and integral part of your body, and as such are vulnerable to your lifestyle choices.

You May Not Be Eating Enough Fiber to Support Your Gut

Eating a lot of processed foods, for instance, compromises your bacteria as processed foods in general destroy healthy microflora and feed harmful bacteria and yeast. Your gut bacteria are also highly sensitive to antibiotics, antibacterial soaps, agricultural chemicals, pollution and chlorinated water.

Since virtually all of us are exposed to these factors, including antibiotics from factory farmed animal products, ensuring your gut bacteria remains balanced must be an ongoing consideration. A high-quality probiotics supplement may be useful in maintaining a well-functioning digestive system if you occasionally stray from your healthy diet or have to take antibiotics.

Gut microbes specializing in fermenting soluble fiber also play an important role in preventing inflammatory disorders as they help to calibrate your immune system.22 The byproducts of this fermentation activity nourish the cells lining your colon and help prevent leaky gut, a condition in which toxins migrate from your gut into your bloodstream, which triggers an inflammatory response.

Although fiber dietary guidelines call for 20 to 30 grams of fiber per day, I believe the ideal amount is much higher, likely twice as high. Eating whole foods, especially vegetables, also naturally provides you with soluble and insoluble fiber to feed the living microorganisms in your gut.

[ad_2]

Source link

قالب وردپرس

Health

Post-vaccine surge? Michigan’s spring coronavirus case spike close to previous year’s autumn high

Editor

Published

on

By

(Natural News) The spike in new Wuhan coronavirus infections recorded in Michigan over the spring is similar to a spike seen during the 2020 fall season. According to a Wall Street Journal analysis, the state’s daily coronavirus case count averaged more than 7,000 for almost two weeks – before taking a slight dip to 6,891 on April 20. This echoed similar figures back in November and December 2020, which saw sharp rises in infections for those two months before plunging.

Back in autumn of last year, Michigan averaged more than 7,000 cases per day for a span of 10 days. New infections dropped slightly, then briefly spiked as the December holidays approached. It then fell to the low 1,000s for the succeeding two months – until ascending again in March.

According to University of Michigan internal medicine professor Dr. Vikas Parekh, the sudden increase in new infections could be attributed to several factors. Among the factors he cited was re-openings, which increased people’s interactions and mobility. Parekh said the loosened restrictions contributed to the spread of the highly contagious U.K. B117 variant.

“As the B117 variant spreads nationally, we will likely see other stats [with] their own surges – although I hope none are as bad as Michigan,” the professor remarked. He continued: “The milestone just tells us we are not yet in the clear, especially as we still have large portions of our population who are not vaccinated yet.”

Parekh also expressed optimism over the lower daily caseloads the Great Lakes State reported. He said he believes both cases and hospitalizations have plateaued and will likely decline soon. The professor commented: “[COVID-19] positivity has been declining now for one week, which is usually a leading indicator of case decline.”

Meanwhile, the state cited younger populations and youth sports, such as basketball, wrestling and hockey, to increase new COVID-19 infections. Because of this, Gov. Gretchen Whitmer called to suspend youth sports and indoor dining in the state. She also exhorted high schools to conduct remote class sessions for two weeks to curb the spread of the pathogen.

Michigan still experienced the spike in cases despite having one of the highest vaccination rates in the country

During the opening stages of the U.S.’s immunization drive against COVID-19, Michigan boasted of having one of the highest vaccination rates nationwide. A report by Bridge Michigan even noted the initial “frenzy for vaccines” that “far exceeded the state’s limited supply.” But things have appeared to turn around for Michigan, as it now struggles to reach the 70 percent vaccination rate needed for herd immunity.

Continue Reading

Health

Scottish mom’s legs turn into a pair of “giant blisters” after first dose of AstraZeneca’s coronavirus vaccine

Editor

Published

on

By

(Natural News) Sarah Beuckmann of Glasgow, Scotland, felt a tingling sensation in her legs and noticed a rash flaring up around her ankles a week after getting her first dose of AstraZeneca’s coronavirus (COVID-19) vaccine on March 18.

She also had flu-like symptoms right after the vaccination.

Beuckmann called her doctor to arrange an appointment the morning she noticed the rash, but by the afternoon her skin was already breaking out into blood-filled blisters. Blisters also appeared on her legs, hands, face, arms and bottom.

“I ended up asking my husband to take me to A&E,” said Beuckmann, referring to “accident and emergency,” the equivalent of an emergency room (ER). “When I got there, my heart rate was sitting at 160bpm, which they were very concerned about. I got put on an ECG machine.”

Doctors determine AstraZeneca’s COVID-19 vaccine triggers the rash

Medics carried out tests for HIV, herpes and other skin conditions to work out what triggered the rash, but all results came back negative. Doctors finally determined that the vaccine caused her rare reaction after carrying out two biopsies.

“Once they found that it was a reaction to the vaccine, they put me on steroids and that really seems to be helping my progress,” said Beuckmann. She had been advised by her doctor not to get the second dose of AstraZeneca’s COVID-19 vaccine because of her reaction.

Beuckmann spent 16 days at Queen Elizabeth University Hospital. She was discharged to recover at home. The 34-year-old mother of one is currently wheelchair-bound due to the bandages on her legs and blisters on the soles of her feet. She may need physiotherapy to help strengthen her leg muscles.

“They are starting to heal and they’re looking a lot better than they were but as the blisters started to get worse, they all sort of merged together,” she said. “I didn’t know what was going on.”

With the blisters merging, her legs have looked like a pair of “giant blisters.” Beuckmann admitted that at one point she feared her legs might have to be amputated.

Dermatologist agrees COVID-19 vaccine causes the blisters

Dr. Emma Wedgeworth, a consultant dermatologist and spokeswoman at the British Skin Foundation, agreed that Beuckmann had likely suffered a reaction to the vaccine.

“Vaccines are designed to activate the immune system. Occasionally people will have quite dramatic activation of their immune systems which, as happened in this case, can manifest in their skin” Wedgeworth told MailOnline. “This poor lady had a very severe reaction, which thankfully is extremely rare.”

It is not clear why Beuckmann, who works in retail, was invited for a vaccine. Scotland’s vaccine rollout was focused on people over the age of 50 when she got vaccinated, although vaccines are available to those who are considered at risk from the virus, or live with someone considered vulnerable.

At least 20 million Briton have had AstraZeneca’s COVID-19 vaccine, which drug regulators say causes a rash in one percent of cases. They say rashes caused by the jab tend to go away within a week.

Continue Reading

Health

Trojan labs? Chinese biotech company offers to build COVID testing labs in six states

Editor

Published

on

By

In 2012, BGI acquired Complete Genomics, a DNA sequencing company and equipment maker. The funds for the $117.6 million purchase were raised from Chinese venture capitals. The company has expanded its footprint globally. According to its website, BGI conducts business in more than 100 countries and areas and has 11 offices and labs in the U.S.

People are concerned about China’s access to American DNA data

Some said that with Complete Genomics providing an American base, BGI would have access to more DNA samples from Americans, helping it compile a huge database of genetic information. Some also worried about the protection of the genetic information’s privacy.

According to a 2019 report from the U.S.–China Economic and Security Review Commission (USCC), BGI “has formed numerous partnerships with U.S. healthcare providers and research organizations to provide large-scale genetic sequencing to support medical research efforts,”

There are three main reasons why many people in the biotech community and government have expressed concerns about China’s access to American DNA data.

In the “60 Minutes” interview, Evanina discussed the very likely scenario in which Chinese companies would be able to micro-target American individuals and offer customized preventative solutions based on their DNA.

Evanina asked: “Do we want to have another nation systematically eliminate our healthcare services? Are we okay with that as a nation?”

The second concern is that China may use DNA to track and attack American individuals. As the USCC report states: “China could target vulnerabilities in specific individuals brought to light by genomic data or health records. Individuals targeted in such attacks would likely be strategically identified persons, such as diplomats, politicians, high-ranking federal officials or military leadership.”

The third concern is that China may devise bioweapons to target non-Asians. Steven Mosher, president of the Population Research Institute, discussed it in his article “What Will China Do With Your DNA?” published by The Epoch Times in March 2019.

He wrote: “We know that the Asian genome is genetically distinct from the Caucasian and African in many ways. … Would it be possible to bioengineer a very virulent version of, say, smallpox, that was easily transmitted, fatal to other races, but to which the Chinese enjoyed a natural immunity? … Given our present ability to manipulate genomes, if such a bio-weapon can be imagined, it can probably – given enough time and resources – be realized.”

An article from Technocracy said: “China’s aggressive collection of American DNA should be doubly alarming because it can only spell one ultimate outcome: biowarfare. That is, genetically engineering viruses or other diseases that will be selectively harmful to U.S. populations.”

Continue Reading

Chat

Trending